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Bet v 1, Biotinylated

Recombinant Betula pendula allergen Bet v 1, Biotinylated was expressed in E. coli and purified by affinity chromatography using a His tag.

BV01-A921BH
250 ug500 ug Bulk Customize

$ 385

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Alternate Names:

Major pollen allergen Bet v 1-A, Allergen Bet v I-A, Bet v 1-A, BETVIA, BETVI


Source:

Betula pendula


UniProt Number:

P15494


Purity:

>80%


Genbank Number:

X15877


Formulation:

Recombinant protein stored in 1x PBS, 5% trehalose solution.


Modifications:

Biotinylated allergens can be directly used with streptavidin-coated beads.
In SignalChem Diagnostics' allergens, biotin is covalently attached at a site away from the IgE-binding region, preserving conformational integrity and immunoreactivity of the protein. This site-specific conjugation provides optimal molecular orientation for better allergen display on solid surfaces and improved assay performance.

References:

1. Breiteneder H, et al: The gene coding for the major birch pollen allergen Betv1, is highly homologous to a pea disease resistance response gene. EMBO J. Jul;8(7):1935-8, 1989.

2. Elsayed S, et al: Purification and N-terminal amino acid sequence of two birch pollen isoallergens (Bet v I and Bet v II). Int Arch Allergy Appl Immunol.;93(4):378-84, 1990.



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