Home   >   Reagents   >    Immunodiagnostics    >    Immunodiagnostics Allergens

Signalchem Product Image

Der p 21/23 Fusion, Biotinylated

Recombinant Dermatophagoides pteronyssinus fusion allergen Der p 21/23 was expressed in E. coli, purified by affinity chromatography using a His tag, and labeled with biotin.

DP22-A941AH
250 ug500 ug Bulk Customize

$ 448

*The image is illustrative and does not necessarily represent the product


Alternate Names:

Mite allergen Der p 21; Major House Dust Mite allergen Der p 23


Source:

Dermatophagoides pteronyssinus


UniProt Number:

Der p 21 Q2L7C5

Der p 23 L7N6F8


Purity:

>80%


Genbank Number:

Der p 21: DQ354124.1
Der p 23: EU414751.1


Formulation:

Recombinant protein stored in 1X PBS, 5% trehalose solution.


Modifications:

Biotinylated allergens can be directly used with streptavidin-coated beads.
In SignalChem Diagnostics' allergens, biotin is covalently attached at a site away from the IgE-binding region, preserving conformational integrity and immunoreactivity of the protein. This site-specific conjugation provides optimal molecular orientation for better allergen display on solid surfaces and improved assay performance.

References:

1. Weghofer M, et al. Characterization of Der p 21, a new important allergen derived from the gut of house dust mites. Allergy. 63:758-67, 2008.

2. Mueller GA, et al: Serological, genomic and structural analyses of the major mite allergen Der p 23. Clin. Exp. Allergy. 46:365-76, 2016.



There are no related publications available for this product.