Custom
Protein
Synthesis
SignalChem Diagnostics provides custom recombinant protein production services for research, assay development, and diagnostic applications. From gene cloning and protein expression to purification and characterization, each project is planned around the biological properties of the target protein and its intended use.
Flexible Expression Options
We offer multiple expression systems to meet the requirements of your target protein and application. Our team helps you select the optimal host and strategy to maximize yield, quality, and scalability.
Every project begins with a consultation and review of your goals. We tailor each plan to your specifications and guide you through every step from sequence to solution.
High-yield production with fast turnaround and cost efficiency
Native-like expression for therapeutic and diagnostic proteins
Baculovirus expression vector system for complex protein folding
Scalable fermentation for soluble recombinant proteins
Recombinant proteins with expertise in allergen production
Projects can begin with a DNA sequence, amino acid sequence, NCBI GenBank accession number, or a customer-provided plasmid. We handle construct design, codon optimization, and cloning as needed to set your project up for success.
Available Services
- Gene cloning and recombinant protein expression
- Protein purification and characterization
- Fusion protein production
- Glycerol-free formulation
- Tag change or removal
- Conjugation and other protein modifications
- Lyophilization
- Endotoxin removal
- Buffer and formulation customization
- Purity and concentration customization
Manufacturing in an ISO 13485-certified facility
A process built for your project
Each custom protein request is evaluated individually to determine technical feasibility and establish an appropriate production strategy.
Project Review
We review your target protein, application requirements, and any available sequence or construct information. Our team discusses project scope, timeline, and deliverables to create a clear plan.
Production Planning
We design the expression construct, optimize codon usage as needed, and select the most suitable expression system. The production strategy, milestones, and quality criteria are defined.
Protein Expression and Purification
We express the protein under optimized conditions and purify it to the desired level. Quality is assessed throughout the process to ensure consistency and performance.
Final Preparation and Delivery
The protein is formulated to your specifications, quality checked, and prepared for shipment. Documentation and data are provided to support your work.
Have a protein target in mind?
Submit the Custom Protein Synthesis request form to
receive a project assessment and quotation.