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Alanyl-tRNA Synthetase (PL-12) Antigen

Recombinant Human Alanyl-tRNA Synthetase (PL-12) Antigen was expressed by baculovirus in Sf9 insect cells and purified by affinity chromatography using a His tag.

ASA01-F23H
100 µg1 mg Bulk Customize

$ 260

*The image is illustrative and does not necessarily represent the product


Alternate Names:

Alanyl-tRNA Synthetase, AlaRS, PL-12 Autoantigen


Formulation:

Protein stored in 20 mM HEPES, pH 8.0, 250 mM NaCl, 20% Glycerol


References:

1. Bunn CC, et al. Autoantibodies against alanyl-tRNA synthetase and tRNAAla coexist and are associated with myositis. J Exp Med. 1986 May 1;163(5):1281-91.

2. Ira N. et al. Clinical manifestations in patients with antibody to PL-12 antigen (alanyl-tRNA synthetase). The American Journal of Medicine. 1990, 88(3): 241-251,

3. García-Lozano JR, et al. Detection of anti-PL-12 autoantibodies by ELISA using a recombinant antigen; study of the immunoreactive region. Clin Exp Immunol. 1998 Nov;114(2):161-5.

Storage and Stability:

Store at –70°C. To avoid repeated handling and multiple freeze/thaw cycles, aliquot product into smaller quantities


Source:

Homo Sapiens (Human)


Host:

Baculovirus-infected Sf9 insect cells


Molecular Weight:

Calculated: 110 kDa
Observed: ~110 kDa


Purity:

The purity was determined to be ≥ 85% by densitometry




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