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Centromere Protein B (CENP-B) Antigen

Recombinant Human Centromere Protein B (CENP-B) Antigen is a tag-free protein expressed by baculovirus in Sf9 insect cells. It is suitable for autoimmune research and IVD assay development for the detection of anti-CENP-B autoantibodies.

CPA01-F23N
100 µg1 mg Bulk Customize

$ 260

*The image is illustrative and does not necessarily represent the product


Alternate Names:

CENPB, Centromere protein B (CENP-B)


References:

1. Earnshaw WC, et al. Molecular cloning of cDNA for CENP-B, the major human centromere autoantigen. J Cell Biol. 1987 Apr;104(4):817-29.

2. Servettaz A, et al. Anti-endothelial cell antibodies from patients with limited cutaneous systemic sclerosis bind to centromeric protein B (CENP-B). Clin Immunol. 2006 Aug;120(2):212-9.

3. Whyte J. et al., Frequency of autoantibodies to a major epitope on the carboxyl terminal fragment of CENP-B in patients with autoimmune disease, British Journal of Rheumatology, 1995, 34(5): 407–412.

Storage and Stability:

Store at –70°C. To avoid repeated handling and multiple freeze/thaw cycles, aliquot product into smaller quantities


Source:

Homo Sapiens (Human)


Host:

Baculovirus-infected Sf9 insect cells


FormulationProtein stored in 20 mM HEPES, pH 7.6, 500 mM NaCl, 20% Glycerol:

Protein stored in 20 mM HEPES, pH 7.6, 500 mM NaCl, 20% Glycerol


Molecular weight:

Calculated: 80 kDa
Observed: ~78 kDa


Purity:

The purity was determined to be ≥ 85% by densitometry




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