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Cytochrome P450 2D6 (LKM) Antigen

Recombinant Human Cytochrome P450 2D6 (LKM) Antigen was expressed by baculovirus in Sf9 insect cells and purified by affinity chromatography using a His tag.

CPA02-F23N
100 µg1 mg Bulk Customize

$ 260

*The image is illustrative and does not necessarily represent the product


Alternate Names:

CYPIID6, Cyochrome P450-DB1


Formulation:

Protein stored in 17 mM HEPES, pH 7.5, 425 mM NaCl, 1 mM DTT, 0.2% Triton X-100, 15% Glycerol


References:

1. Manns MP, et al. Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is cytochrome P450db1. J Clin Invest. 1989 Mar;83(3):1066-72.

2. Liberal R, et al. Clinical significance of autoantibodies in autoimmune hepatitis. J Autoimmun. 2013 Oct; 46:17-24.

3. Bogdanos D, et al. Autoimmune liver serology: current diagnostic and clinical challenges. World J. Gastroenterol. 2008; 14:3374.

Storage and Stability:

Store at –70°C. To avoid repeated handling and multiple freeze/thaw cycles, aliquot product into smaller quantities.


Source:

Homo Sapiens (Human)


Host:

Baculovirus-infected Sf9 insect cells


Molecular Weight:

Calculated: 55.6 kDa
Observed: ~52 kDa


Purity:

The purity was determined to be ≥ 85% by densitometry




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