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Human Histidyl-tRNA-Synthetase (Jo-1) Antigen

Recombinant Human Histidyl-tRNA Synthetase (Jo-1) Antigen is a tag-free protein was expressed by baculovirus in Sf9 insect cells. It is intended for use in autoimmune research and IVD assay development for the detection of anti-Jo-1 autoantibodies.

HHA01-F23N
100 µg1 mg Bulk Customize

$ 260

*The image is illustrative and does not necessarily represent the product


Alternate Names:

Histidyl-tRNA synthetase, Jo-1 Autoantigen, HisRS


Formulation:

Protein stored in 20 mM HEPES, pH 7.5, 250 mM NaCl, 20% Glycerol


References:

1. Mathews MB, et al. Myositis autoantibody inhibits histidyl-tRNA synthetase: a model for autoimmunity. Nature. 1983;304(5922):177-179.

2. Dang CV, et al. Histidyl-tRNA synthetase, the myositis Jo-1 antigen, is cytoplasmic and unassociated with the cytoskeletal framework. Exp Cell Res. 1986;164(1):261-266.

3. Ramsden DA et al. Epitope mapping of the cloned human autoantigen, histidyl-tRNA synthetase. J Immunol. 1989;143(7):2267-2272.

Storage and Stability:

Store at –70°C. To avoid repeated handling and multiple freeze/thaw cycles, aliquot product into smaller quantities


Source:

Homo Sapiens (Human)


Host:

Baculovirus-infected Sf9 insect cells


Molecular Weight:

Calculated: 58 kDa
Observed: ~55 kDa


Purity:

The purity was determined to be ≥ 85% by densitometry




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