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SLA/LP Antigen

Recombinant Human SLA/LP Antigen was expressed in E. coli and purified by affinity chromatography using a His tag.

SLA01-F23H
100 µg1 mg Bulk Customize

$ 260

*The image is illustrative and does not necessarily represent the product


Alternate Names:

Sep (O-phosphoserine) tRNA:Sec (Selenocysteine) tRNA Synthase, Soluble Liver Antigen/Liver Pancreas Antigen (SLA/LP), SLA Autoantigen


Formulation:

Protein stored in 20 mM HEPES, pH 7.5, 0.01 mM EDTA, 0.02% SDS


References:

1. Wies I, et al. Identification of target antigen for SLA/LP autoantibodies in autoimmune hepatitis. The Lancet, 2000, 355(9214):1510-1515.

2. Baeres M, et al. Establishment of standardised SLA/LP immunoassays: specificity for autoimmune hepatitis, worldwide occurrence, and clinical characteristics. Gut. 2002 Aug;51(2):259-64.

3. Martin V., et al. SLA/LP/tRNP (Ser) Sec antigen in autoimmune hepatitis: Identification of the native protein in human hepatic cell extract, Journal of Autoimmunity. 2010, 34(1): 59-65.

Storage and Stability:

Store at –70°C. To avoid repeated handling and multiple freeze/thaw cycles, aliquot product into smaller quantities


Source:

Homo Sapiens (Human)


Host:

E. coli


Molecular Weight:

Calculated: 51 kDa
Observed: ~50 kDa


Purity:

The purity was determined to be ≥ 85% by densitometry




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