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SRP54 Antigen

Recombinant Human SRP54 Antigen was expressed by baculovirus in Sf9 insect cells and purified by affinity chromatography using a His tag.

SPR01-F23H

100 µg1 mg Bulk Customize

$ 260

*The image is illustrative and does not necessarily represent the product


Alternate Names:

Signal recognition particle 54 kDa protein


Formulation:

Protein stored in 6 mM HEPES, pH 8.0, 320 mM NaCl, 5 mM DTT, 1 mM EDTA, 0.16 mM GDP, 20% Glycerol


References:

1. Römisch K, et al. Human autoantibodies against the 54 kDa protein of the signal recognition particle block function at multiple stages. Arthritis Res Ther. 2006;8(2): R39.

2. Watanabe Y, et al. Clinical features and prognosis in anti‐SRP and anti‐HMGCR necrotising myopathy. J Neurol Neurosurg Psychiatry 2016; 87: 1038–1044.

3. Palterer B., et al. Bench to bedside review of myositis autoantibodies. Clin Mol Allergy (2018) 16:5

Storage and Stability:

Store at –70°C. To avoid repeated handling and multiple freeze/thaw cycles, aliquot product into smaller quantities.


Source:

Homo Sapiens (Human)


Host:

sf9


Molecular Weight:

Calculated: 56.5 kDa
Observed: 56 kDa


Purity:

The purity was determined to be ≥ 85% by densitometry





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